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Heterogeneity of Renin and Renin Substrate explores the complexities of the renin-angiotensin system (RAS), focusing on the diverse forms of renin and its substrate, angiotensinogen. This book delves into the biochemical, physiological, and clinical implications of these variations, examining how different renin isoforms and angiotensinogen variants influence blood pressure regulation, electrolyte balance, and cardiovascular function.
The text covers the synthesis, processing, and secretion of renin, as well as the structure, function, and regulation of angiotensinogen. Furthermore, the book explores the role of these molecules in various pathological conditions, including hypertension, heart failure, and kidney disease. It is a valuable resource for researchers and clinicians interested in understanding the intricacies of the renin-angiotensin system and its relevance to human health.
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